発表論文(2000年〜)
last up date→ 2024/4/3



Time-Course Metabolomic Analysis: Production of Betaine Structural Analogs by Fungal Fermentation of Seaweed.
N. Inoue, K. Tsuge, T. Yanagita, A. Oikawa, K. Nagao, Metabolites, 14: 201 (2024) [PubMed]

Ozonated olive oil intake attenuates hepatic steatosis in obese db/db mice.
Y. Kato, M. Sakoh, T. Nagai, A. Yoshida, H. Ishida, N. Inoue, T. Yanagita, K. Nagao, J. Oleo Sci., 73: 231-237 (2024) [PubMed]



Identification of genes regulated by lipids from seaweed Susabinori (Pyropia yezoensis) involved in the improvement of hepatic steatosis: Insights from RNA-Seq analysis in obese db/db mice.
S. Iizasa , K. Nagao, K. Tsuge, Y. Nagano, T. Yanagita, PLoS One, 18(12): e0295591 (2023) [PubMed]



脂質の吸収・代謝と栄養・機能.
永尾晃治, オレオサイエンス, 22: 514-520 (2022) [Publisher]

メタボリックシンドロームと機能性脂質.
永尾晃治, 日本食品安全協会会誌, 17: 144-149 (2022) [Publisher]

Dried and fermented powders of edible algae (Neopyropia yezoensis) attenuate hepatic steatosis in obese mice.
K. Nagao, N. Inoue, K. Tsuge, A. Oikawa, T. Kayashima, T. Yanagita, Molecules, 27: 2640 (2022) [PubMed]

Comparison of lipoprotein cholesterol levels in golden Syrian hamster administrated trans-octadecenoic acid positional isomers.
K. Nagao, K. Yoshinaga, T. Nagai, H. Mizobe, A. Yoshida, F. Beppu, S. Tanaka, N. Gotoh, J. Oleo Sci., 71: 609-618 (2022) [PubMed]

Ozonated olive oil alleviates hepatic steatosis in obese Zucker (fa/fa) rats.
Y. Kato, M. Sakoh, T. Nagai, A. Yoshida, H. Ishida, N. Inoue, T. Yanagita, K. Nagao, J. Oleo Sci., 71: 599-607 (2022) [PubMed]



The cholesterol metabolite cholest-5-en-3-one alleviate hyperglycemia and hyperinsulinemia in obese (db/db) mice.
K. Nagao, N. Inoue, K. Suzuki, T. Shimizu, T. Yanagita, Metabolites, 12: 26 (2022) Published: 29 December 2021 [PubMed]



Hydrophilic β-conglycinin peptide reduces hepatic triglyceride accumulation in obese model OLETF rats.
S. Wanezaki, S. Saito, N. Inoue, N. Tachibana, T. Yanagita, K. Nagao, Food Sci. Technol. Res., 26: 797-803 (2020) [Publisher]

Anti-stress effects of rosemary (Rosmarinus officinalis L.) leaf extract on intestinal goblet cells and immobility of forced-swimming test in BALB/c mice.
T. Kayashima, K. Nagao, M. Umino, H. Kaikiri, S. Shibata, K. Matsubara, Biosci. Biotechnol. Biochem., 84: 2385-2389 (2020) [PubMed]

脂質構造異性体による nutraceutical delivery.
永尾晃治, 生物工学 98: 533-535 (2020) [Publisher]

Eicosapentaenoic acid-containing polar lipids from seaweed Susabinori (Pyropia yezoensis) alleviate hepatic steatosis in obese db/db mice.
T. Yanagita, K. Tsuge, M. Koga, N. Inoue, K. Nagao, Archiv. Biochem Biophys., 691: 108486 (2020) [PubMed]

麹グリコシルセラミドによるコレステロール代謝改善.
北垣浩志,浜島浩史,中山二郎,永尾晃治, バイオサイエンスとインダストリー 78: 410-411 (2020) [Publisher]

Soy β-conglycinin peptide attenuates obesity and lipid abnormalities in obese model OLETF rats.
S. Wanezaki, S. Saito, N. Inoue, N. Tachibana, B. Shirouchi, M. Sato, T. Yanagita, K. Nagao, J. Oleo Sci., 69: 495-502 (2020) [PubMed]



麹に含まれるグリコシルセラミドの健康機能.
山本裕貴,浜島浩史,田中優,藤丸裕貴,阪本真由子,宮川幸,西向めぐみ,柳田晃良,中村強,光武進,永尾晃治,中山二郎,北垣浩志, 生物工学 97: 182-184 (2019) [Publisher]

Koji glycosylceramide commonly contained in Japanese traditional fermented foods alters cholesterol metabolism in obese mice.
H. Hamajima, M. Tanaka, M. Miyagawa, M. Sakamoto, T. Nakamura, T. Yanagita, M. Nishimukai, S. Mitsutake, J. Nakayama, K. Nagao, H. Kitagaki, Biosci. Biotechnol. Biochem., 83:1514-1522 (2019) [PubMed]

Evaluating the content and distribution of trans fatty acid isomers in foods consumed in Japan.
N. Gotoh, K. Yoshinaga, S. Kagino, Y. Katoh, Y. MIzuno, F. Beppu, T. Nagai, H. Mizobe, A. Yoshida, K. Nagao, J. Oleo Sci., 68: 193-202 (2019) [PubMed]



Metabolism of Natural Highly Unsaturated Fatty Acid, Tetracosahexaenoic Acid (24:6n-3), in C57BL/KsJ-db/db Mice.
N. Gotoh, K. Nagao, H. Ishida, K. Nakamitsu, K. Yoshinaga, T. Nagai, F. Beppu, H. Watanabe, T. Yanagita, J. Oleo Sci., 67:1597-1607 (2018) [PubMed]

Study on the trans fatty acid formation in oil by heating using model compounds.
N. Gotoh, S. Kagino, K. Yoshinaga, H. Mizobe,T. Nagai, A. Yoshida, F. Beppu, K. Nagao, J. Oleo Sci., 67: 273-281 (2018) [PubMed]



Comparison of the Effect of trans Fatty Acid Isomers on Apolipoprotein A1 and B Secretion in HepG2 Cells..
K. Nagao, K. Yoshinaga, T. Nagai, H. Mizobe, A. Yoshida, F. Beppu, N. Gotoh, J. Oleo Sci., 66: 1175-1181 (2017) [PubMed]

麹で造られる醸造食品のグリコシルセラミド含量定量手法の検討とそれを用いた定量.
阪本真由子,酒谷真以, Ferdouse J.,浜島浩史,柘植圭介,西向めぐみ,柳田晃良,永尾晃治,光武進,北垣浩志, 日本醸造協会誌 112: 655-662 (2017) [Publisher]

Pterostilbene, a dimethylated analog of resveratrol, promotes energy metabolism in obese rats.
K. Nagao, T. jinnouch, S. Kai, T. Yanagita, J. Nutr. Biochem, 43: 151-155 (2017) [PubMed]

Soy Protein Isolate Suppresses Lipodystrophy-induced Hepatic Lipid Accumulation in Model Mice.
K. Nagao, A. Matsumoto, S. Kai, T. Kayashima, T. Yanagita, J. Oleo Sci., 66: 161-169 (2017) [PubMed]



Japanese Traditional Dietary Fungus Koji Aspergillus Oryzae Functions as a Prebiotic for Blautia Coccoides through Glycosylceramide.
H. Hamajima, H. Matsunaga, A. Fujikawa, T. Sato, S. Mitsutake, T. Yanagita, K. Nagao, J. Nakayama, H. Kitagaki, Springerplus, 5: 1321 (2016) [PubMed]

食環境を利用したメタボリックシンドロームの予防・改善の可能性.
永尾晃治,柳田晃良, 粥状動脈硬化症,アトムス,戸田隆義編, 134-142 (2016) [Publisher]

Probiotic Lactobacillus gasseri SBT2055 improves glucose tolerance and reduces body weight gain in rats by stimulating energy expenditure.
B. Shirouchi, K. Nagao, M. Umegatani, A. Shiraishi, Y. Morita, S. Kai, T. Yanagita, A. Ogawa, Y. Kadooka, M. Sato, Br. J. Nutr., 116: 451-458 (2016) [PubMed]

Chemical analysis of the sugar moiety of monohexosylceramide contained in koji, Japanese traditional rice fermented with Aspergillus.
H. Hamajima, H. Matsunaga, M. Yamashiro, S. Tan, S. Kumagai, N. Hayashi, K. Nagao, S. Mitsutake, H. Kitagaki, Fermentation, 2: 2 (2016) [Publisher]



Trans-octadecenoic Acid Positional Isomers Have Different Accumulation and Catabolism Properties in Mice.
F. Beppu, M. Asanuma, Y. Kawamura, T. Nagai, K. Yoshinaga, H. Mizobe, K. Kojima, S. Kasatani, K. Nagao, A. Kubo, J. Kanda, N. Gotoh, J. Oleo Sci., 64: 1159-1167 (2015) [PubMed]

Generation of tetracosahexaenoic acid in marine organisms.
R. Suo, H. Li, K. Yoshinaga, T. Nagai, H. Mizobe, K. Kojima, K. Nagao, F. Beppu, N. Gotoh, J. Oleo Sci., 64: 721-727 (2015) [PubMed]

Glucosylceramide Contained in Koji Mold-Cultured Cereal Confers Membrane and Flavor Modification and Stress Tolerance to Saccharomyces cerevisiae during Coculture Fermentation.
K. Sawada, T. Sato, H. Hamajima, L. Jayakody, M. Hirata, M. Yamashiro, M. Tajima, S. Mitsutake, K. Nagao, K. Tsuge, F. Abe, K. Hanada,.H. Kitagaki, Appl. Environ. Microb., 81: 3688-3698 (2015) [PubMed]

Functional lipids in metabolic syndrome.
K. Nagao, T. Yanagita, J. Nutr. Sci. Vitaminol., 61: S159-161 (2015) [PubMed]

Soy β-conglycinin improves obesity-induced metabolic abnormalities in a rat model of nonalcoholic fatty liver disease.
S. Wanezaki, N. Tachibana, M. Nagata, S. Saito, K. Nagao, T. Yanagita, M. Kohno, Obes. Res. Clin. Prac., 9: 168-174 (2015) [PubMed]

Differential effects of triacylglycerol positional isomers containing n-3 series highly unsaturated fatty acids on lipid metabolism in C57BL/6J mice.
K. Yoshinaga, K. Sasaki, H. Watanabe, K. Nagao, N. Inoue, B. Shirouchi, T. Yanagita, T. Nagai, H. Mizobe, K. Kojima, F. Beppu, N. Gotoh, J. Nutr. Biochem., 26: 57-63 (2015) [PubMed]



脂質の栄養と代謝.
永尾晃治, オレオサイエンス, 14: 563-567 (2014) [Publisher]

A comparison of the lipid-lowering effects of four different n-3 highly unsaturated fatty acids in HepG2 cells.
K. Nagao, K. Nakamitsu, H. Ishida, K. Yoshinaga, T. Nagai, H. Mizobe, K. Kojima, T. Yanagita, F. Beppu, N. Gotoh, J. Oleo Sci., 63: 979-985 (2014) [PubMed]

Impact of fasting time on hepatic lipid metabolism in nutritional animal studies.
I. Ikeda, K. Metokia, T. Yamahiraa, M. Kato, N. Inoue, K. Nagao, T. Yanagita, H. Shirakawa, M. Komai, Biosci. Biotechnol. Biochem., 78: 1584-1591 (2014) [PubMed]
*This publication was given an Award for Excellence to Authors Publishing in Biosci. Biotechnol. Biochem. in 2014.

エレクトロスプレーイオン化質量分析(ESI-MS/MS)による芋焼酎粕に含まれるグルコシルセラミドの構造決定.
澤田和敬,中畑絵里子,柘植圭介,平田みよ,熾和則,永尾晃治,北垣浩志, 日本醸造協会誌 109: 535-542 (2014) [Publisher]

Unavailability of liver triacylglycerol increases serum cholesterol concentration induced by dietary cholesterol in exogenously hypercholesterolemic (ExHC) rats.
Y. Tanaka, K. Nagao, H. Nakagiri, T. Nagaso, Y. Iwasa, H. Mori, M. Asahina, K. Imaizumi, M. Sato, Lipids Health Dis., 13: 19 (2014) [PubMed]

Quantitaion and structural determination of glucosylceramides contained in sake lees.
K. Takahashi, K. Izumi, E. Nakahata, M. Hirata, K. Sawada, K. Tsuge, K. Nagao, H. Kitagaki, J. Oleo Sci., 63: 15-23 (2014) [PubMed]



Dietary phosphatidylinositol protects C57BL/6 mice from concanavalin A-induced liver injury by modulating immune cell functions.
M. Inafuku, K. Nagao, A. Inafuku, T. Yanagita, N. Taira, T. Toda, H. Oku, Mol. Nutr. Food Res., 57: 1671-1679 (2013) [PubMed]

Effect of Mukitake mushroom (Panellus serotinus) on the pathogenesis of lipid abnormalities in obese, diabetic ob/ob mice.
N. Inoue, M. Inafuku, B. Shirouchi, K. Nagao, T. Yanagita, Lipids Health Dis., 12: 18 (2013) [PubMed]

オメガ3脂肪酸の栄養化学.
永尾晃治, BIO INDUSTRY 30, 5-10 (2013) [Publisher]

Effect of dietary resveratrol on the metabolic profile of nutrients in obese OLETF rats.
K. Nagao, T. Jinnouchi, S. Kai, T. Yanagita, Lipids Health Dis., 12: 8 (2013) [PubMed]

油脂と健康.
柳田晃良, 永尾晃治, 人と食と自然シリーズ3・脂肪の功罪と健康,建帛社,京都健康フォーラム監修・河田照雄編, 29-47 (2013) [Publisher]



Structural Determination of Glucosylceramides in the Distillation Remnants of Shochu, the Japanese Traditional Liquor, and Its Production by Aspergillus kawachii.
M. Hirata, T. Tsuge, L. Jayakody, Y. Urano, K. Takahashi, K. Sawada, S. Inaba, K. Nagao, H. Kitagaki, J. Agric. Food Chem., 60: 11473-11482 (2012) [PubMed]

Mechanisms underlying the decreased hepatic triacylglycerol and cholesterol by dietary bitter melon extract in the rat.
GV. Senanayake, N. Fukuda, S. Nshizono, YM. Wang, K. Nagao, T. Yanagita, M. Iwamoto, H. Ohta, Lipids, 47: 495-503 (2012) [PubMed]

メタボリックシンドロームにおける機能性脂質の活用.
永尾晃治, 生物試料分析, 35: 113-118 (2012) [Publisher]

Effects of lotus root (edible rhizome of Nelumbo nucifera) on the deveolopment of nonalcoholic fatty liver disease in obese diabetic db/db mice.
Y. Tsuruta, K. Nagao, B. Shirouchi, S. Nomura, K. Tsuge, K. Koganemaru, T. Yanagita, Biosci. Biotechnol. Biochem., 76: 462-466 (2012) [PubMed]

Protective effects of fractional extracts from Panellus serotinus on nonalcoholic fatty liver disease in obese, diabetic db/db mice.
M. Inafuku, K. Nagao, S. Nomura, B. Shirouchi, N. Inoue, N. Nagamori, H. Nakayama, T. Toda, T. Yanagita, Br. J. Nutr., 107: 639-646 (2012) [PubMed]



Effect of Peucedanum japonicum Thunb on the expression of obesity-related genes in mice on a high-fat diet.
N. Nukitrangsan, T. Okabe, T. Toda, M. Inafuku, H. Iwasaki, T. Yanagita, H. Oku, J. Oleo Sci., 60: 527-536 (2011) [PubMed]

Polyphenolic extract of lotus root (edible rhizome of Nelumbo nucifera) alleviates hepatic steatosis in obese diabetic db/db mice.
Y. Tsuruta, K. Nagao, S. Kai, T. Yoshimura, K. Tsuge, K. Koganemaru, T. Yanagita, Lipids Health Dis., 10: 202 (2011) [PubMed]

Effect of liver X receptor agonist on deposition and lymphatic absorption of plant sterols in stroke-prone spontaneously hypertensive rats that have a mutation in ATP-binding cassette transporter g5.
T. Hamada, M. Kudo, M. Sato, N. Inoue, K. Nagao, K. Imaizumi, I. Ikeda, Biosci. Biotechnol. Biochem., 75: 2359-2363 (2011) [PubMed]

Effect of Vaccinium ashei reade leaf extracts on lipid metabolism in obese OLETF rats.
N. Inoue, K. Nagao, S. Nomura, B. Shirouchi, M. Inafuku, H. hirabaru, N. Nakahara, S. Nishizono, T. Tanaka, T. Yanagita, Biosci. Biotechnol. Biochem., 75: 2304-2308 (2011) [PubMed]

Screening of soy protein-derived hypotriglyceridemic di-peptides in vitro and in vivo.
N. Inoue, K. Nagao, K. Sakata, N. Yamano, PER. Gunawardena, SY Han, T. Matsui, T. Nakamori, H. Furuta, K. Takamatsu, T. Yanagita, Lipids Health Dis., 10: 85 (2011) [PubMed]

Docosahexaenoic acid containing phosphatidylcholine alleviates obesity-related disorders in obese rats.
B. Shirouchi, K. Nagao, T. Yanagita, Omega-3 Oils: Applications in Functional Foods, ed. by EM. Hernandez, M. Hosokawa, AOCS press, USA, 205-212, (2011) [Publisher]

Suppressive effects of Bunashimeji (Hypsizigus marmoreus) on triacylglycerol accumulation in orotic acid-treated growing rats.
M. Ohtsuki, K. Morishima, K. Umeshita, N. Ohkubo, N. Niwa, T. Yanagita, Y. Furuichi, J. Integ. Study Dietary Habits , 22: 20-27 (2011) [Publisher]

New phenolic compounds from Camellia sinensis L. leaves fermented with Aspergillus sp.
RA. Wulandari, M. Amano, T. Yanagita, T. Tanaka, I. Kouno, D. Kawamura, K. Ishimaru, J. Nat. Med., 65: 594-597 (2011) [PubMed]

Study on possible mechanism of orotic acid-induced fatty liver in rats.
YM. Wang, XQ Hu, Y. Xue, ZJ. Li, T. Yanagita, CH. Xue, Nutrition, 27: 571-575 (2011) [PubMed]



ムキタケ(Panellus serotinus)の抗メタボリックシンドローム作用.
柳田晃良, 永尾晃治, New Food Industry, 52: 13-17 (2010) [Publisher]

Physiological effects of dietary PIPS soybean-derived phospholipid in obese Zucker (fa/fa) rats.
B. Shirouchi, K. Nagao, K. Furuya, M. Shiojiri, X. Liu, T. Yanagita, Biosci. Biotechnol. Biochem., 74: 2333-2335 (2010) [PubMed]

Effects of citrus auraptene (7-geranyloxycoumarin) on hepatic lipid metabolism in vitro and in vivo.
K. Nagao, N. Yamano, B. Shirouchi, N. Inoue, S. Murakami, T. Sasaki, T. Yanagita, J. Agric. Food Chem., 58: 9028-9032 (2010) [PubMed]

Dietary phosphatidylinositol in metabolic syndrome.
B. Shirouchi, K. Nagao, T. Yanagita, Biocatalysis and Biomolecular Engineering , ed. by C.T. Hou, J.F. Shaw, John Wiley & Sons, Inc., USA, 165-174 (2010) [Publisher]

Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow.
R. Shiraishi, R. Iwakiri, T. Fujise, T. Kuroki, T. Kakimoto, T. Takashima, Y. Sakata, S. Tsunada, Y. Nakashima, T. Yanagita, K. Fujimoto, J. Gastroenterol., 45: 625-635 (2010) [PubMed]

Physiological Functions of iso-type Short-Chain Fatty Acid and Omega 3 Polyunsaturated Fatty Acids Containing Oil in Obese OLETF Rats.
B. Shirouchi, K. Nagao, K. Furuya, T. Nagai, K. Ichioka, S. Tokairin, Y. Iida, T. Yanagita , J. Oleo Sci., 59: 299-305 (2010) [PubMed]

Mukitake mushroom (Panellus serotinus) alleviates nonalcoholic fatty liver disease through the suppression of monocyte chemoattractant protein 1 production in db/db mice.
K. Nagao, N. Inoue, M. Inafuku, B.Shirouchi, T. Morooka, S.Nomura, N. Nagamori, T. Yanagita, J. Nutr. Biochem., 21: 418-423 (2010) [PubMed]

Comparative Study of the Effect of Basal Diet Formulation, Dietary Fat and Cholesterol Levels on the Development of Aortic Atherosclerotic Lesions in B6.KOR-Apoeshl Mice.
T. Okabe, T. Toda, N.Nukitrangsan, M. Inafuku, H. Iwasaki, T. Yanagita, H. Oku, J. Oleo Sci., 59: 161-167 (2010) [PubMed]

Dietary saponins of sea cucumber alleviate orotic acid-induced fatty liver in rats via PPAR alpha and SREBP-1c signaling.
XQ. Hu, YM. Wang, JF. Wang, Y. Xue, ZJ. Li, K. Nagao, T. Yanagita, CH. Xue, Lipids Health Dis., 9: 25 (2010) [PubMed]

The mechanism of dietary cholesterol effects on lipids metabolism in rats.
YM. Wang, B. Zhang, Y. Xue, ZJ. Li, JF. Wang, CH. Xue, T. Yanagita, Lipids Health Dis., 9: 4 (2010) [PubMed]

Medium-chain fatty acids: Functional lipids for the prevention and treatment of the metabolic syndrome.
K. Nagao, T. Yanagita, Pharmacol. Res., 61: 208-212 (2010) [PubMed]

機能性脂質によるメタボリックシンドロームの予防・改善に関する研究.
永尾晃治, 日本栄養・食糧学会誌, 63: 3-7 (2010) [Publisher]



Effect of Three Kinds of Highly Purified n-3 Series Highly Unsaturated Fatty Acids on Lipid Metabolism in C57BL/KsJ-db/db Mice.
N. Gotoh, K.Nagao, S. Onoda, B. Shirouchi, K. Furuya, T. Nagai, H. Mizobe, K. Ichioka, H. Watanabe, T. Yanagita, S. Wada, J. Agric. Food Chem., 57: 11047-11054 (2009) [PubMed]

Dietary soy protein isolate and its undigested high molecular fraction upregulate hepatic ATP-binding cassette transporter G5 and ATP-binding cassette transporter G8 mRNA and increase biliary secretion of cholesterol in rats.
I. Ikeda, M. Kudo, T. Hamada, K. Nagao, Y. Oshiro, M. Kato, T. Sugawara, T. Yamahira, H. Ito, S. Tamaru, M. Sato, K. Imaizumi, S. Nagaoka, T. Yanagita, J. Nutr. Sci. Vitaminol., 55: 252-256 (2009) [PubMed]

Branched-Chain Fatty Acid as a Functional Lipid.
H. Oku, T. Yanagita, Biocatalysis and Agricultural Biotechnology , ed. by C.T. Hou, J.F. Shaw, CRC press, USA, 259-267 (2009) [Publisher]

Beneficial effects of conjugated linoleic acid.
K. Koba, T. Yanagita, Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions, ed. by Y. Mine, K. Miyashita, F. Shahidi, John Wiley & Sons, Inc., USA, 85-96 (2009) [Publisher]

Linoleic acid-menthyl ester reduces the secretion of apolipoprotein B100 in HepG2 cells.
N. Inoue, N. Yamano, K. Sakata, K. Arao, T. Kobayashi, T. Nagao, Y. Shimada, K. Nagao, T. Yanagita, J. Oleo Sci., 58: 171-175 (2009) [PubMed]

The sulfated polysaccharide porphyran reduces apolipoprotein B100 secretion and lipid synthesis in HepG2 cells.
N. Inoue, N. Yamano, K. Sakata, K. Nagao, Y. Hama, T. Yanagita, Biosci. Biotechnol. Biochem., 73: 447-449 (2009) [PubMed]

Effect of dietary phosphatidylinositol on cholesterol metabolism in Zucker (fa/fa) rats.
B. Shirouchi, K. Nagao, K. Furuya, N. Inoue, M. Inafuku, M. Nasu, K. Otsubo,S. Koga, H. Matsumoto, T. Yanagita, J. Oleo Sci., 58: 111-115 (2009) [PubMed]

共役リノール酸の臨床的課題.
柳田晃良, 永尾晃治, The Lipid, 20: 78-81 (2009) [Publisher]



Cholesterol lowering effect of sulfur-containing amino acids added to a soybean protein diet in rats.
M. Taniguchi, K. Nagao, K. Inoue, K. Imaizumi, J. Nutr. Sci. Vitaminol., 54: 448-453 (2008) [PubMed]

Taurine reduces the secretion of apolipoprotein B100 and lipids in HepG2 cells.
T. Yanagita, S.Y. Han, Y. Hu, K. Nagao , H. Kitajima, S. Murakami, Lipids Health Dis., 7: 38 (2008) [PubMed]

機能性油脂によるメタボリックシンドロームの予防・改善.
永尾晃治, 柳田晃良, 科学と工業, 493-498 (2008) [Publisher]

Evaluation of the physiological function of docosahexaenoic acid in diet-induced lipodystrophy model mice.
T. Yanagita, K. Nagao, Biocatalysis and Bioenergy, ed. by C.T. Hou, J.F. Shaw, John Wiley & Sons, Inc., USA, 405-415 (2008) [Publisher]

Effect of Vaccinium ashei reade leaves on lipid metabolism in Otsuka Long-Evans Tokushima Fatty rats.
K. Nagao, K. Higa, B. Shirouchi, S. Nomura, N. Inoue, M. Inafuku, T. Yanagita, Biosci. Biotechnol. Biochem., 72: 1619-1622 (2008) [PubMed]

共役リノール酸の健康影響.
柳田晃良, 永尾晃治, 食品機能性の科学, 555-558 (2008) [Publisher]

Dietary phosphatidylinositol prevents the development of nonalcoholic fatty liver disease in Zucker (fa/fa) rats.
B. Shirouchi, K. Nagao, N. Inoue, K. Furuya, S. Koga, H. Matsumoto, T. Yanagita, J. Agrc. Food Chem., 56: 2375-2379 (2008) [PubMed]

Effect of leptin infusion on insulin sensitivity and lipid metabolism in diet-induced lipodystrophy model mice.
K. Nagao , N. Inoue , Y. Ujino , K. Higa , B. Shirouchi , Y.M. Wang, T. Yanagita, Lipids Health Dis., 7: 8 (2008) [PubMed]

Bioactive lipids in metabolic syndrome.
K. Nagao, T. Yanagita, Prog. Lipid Res., 47: 127-146 (2008) [PubMed]
*This publication was given an Elsevier Top Cited Article 2008-2010 Award.

Functional lipids and the prevention of the metabolic syndrome.
T. Yanagita, K. Nagao, Asia Pac. J. Clin. Nutr., 17: 189-191 (2008) [PubMed]



Biological effects of conjugated-linoleic acid.
YS. Huang, T. Yanagita, K. Nagao, K. Koba, Fatty Acids in Foods and Their Health Implications III., ed. by C.K. Chow, CRC press, USA, 825-836 (2007) [Publisher]

Behavior of N-methylcarbamate pesticides during refinement processing of edible oils. [Article in Japanese]
T. Fukazawa, T. Kobayashi, S. Tokairin, K. Chimi, T. Maruyama, T. Yanagita, J. Oleo Sci., 56: 65-71 (2007) [PubMed]

リン脂質研究の新展開.
城内文吾, 永尾晃治, 柳田晃良, Foods Research, 630: 32-35 (2007) [Publisher]

Effect of Vaccinium ashei reade leaves on angiotensin converting enzyme activity in vitro and on systolic blood pressure of spontaneously hypertensive rats in vivo.
H. Sakaida, K. Nagao, K. Higa, B. Shirouchi, N. Inoue, F. Hidaka, T. Kai, T. Yanagita, Biosci. Biotechnol. Biochem., 71: 2335-2337 (2007) [PubMed]

Effect of dietary omega3-PC on obesity-related disorders in obese OLETF rats.
B. Shirouchi, K. Nagao, N. Inoue, T. Ohkubo, H. Hibino, T. Yanagita, J. Agrc. Food Chem., 55, 7170-7176 (2007)
*This publication was given an AOCS Phospholipid Division Award for Best Papar.

C57BL/6Jマウス脂質代謝に及ぼすブナシメジの効果.
大槻誠, 梅下和彦, 苔庵泰志, 西井孝文, 板倉元, 柳田晃良, 久松眞, 古市幸生, 日本食品科学工学会誌, 54:167-172 (2007) [Publisher]

機能性脂質の研究と応用.
柳田晃良, Foodstyle21, 11:31-33 (2007) [Publisher]

CLAの生理活性と応用.
井上奈穂, 永尾晃治, 柳田晃良, Foodstyle21, 11:49-51 (2007) [Publisher]



Conjugated linoleic acid in hypertension.
T. Yanagita, K. Nagao, N. Inoue,YM. Wang, Advances in conjugated linoleic acid research, Vol.3., ed. by M.P. Yurawecz, J.K.G. Kramer, O. Gudmundsen, M.W. Pariza, S. Banni, AOCS press, USA, 171-181 (2006) [Publisher]

Dietary conjugated linoleic acid lowered tumor necrosis factor-alpha content and altered expression of genes-related to lipid metabolism and insulin sensitivity in the skeletal muscle of Zucker rats.
N. Inoue, K. Nagao, Y.M. Wang, H. Noguchi, B. Shirouchi, T. Yanagita, J. Agrc. Food Chem., 54:7935-7939 (2006) [PubMed]

ラット脂質代謝に及ぼす食用キノコの作用.
大槻誠, 梅下和彦, 苔庵泰志, 西井孝文, 板倉元, 柳田晃良, 古市幸生, 日本食品科学工学会誌, 53:612-618 (2006) [Publisher]

機能性脂質.
柳田晃良, 池田郁男, 永尾晃治, 生物と化学, 44:563-568 (2006) [Publisher]

Campest-5-en-3-one, an oxidized derivative of campesterol, activates PPAR-alpha, promotes energy consumption and reduces visceral fat deposition in rats.
I. Ikeda, R. Konno, T. Shimizu, T. Ide, N. Takahashi, T. Kawada, K. Nagao, N. Inoue, T. Yanagita, T. Hamada, Y. Morinaga, H. Tomoyori, K. Imaizumi, K. Suzuki, Biochim. Biophys. Acta, 1760: 800-807 (2006) [PubMed]

Dietary conjugated linoleic acid and metabolic syndromes.
K. Nagao, YM. Wang, N. Inoue, T. Yanagita, Dietary Fats and Risk of Chronic Disease., ed. by Y.S. Huang, T. Yanagita, H. Knapp, AOCS press, USA, 80-91 (2006) [Publisher]

Isomer-specific anti-obese and hypolipidemic properties of conjugated linoleic acid in obese OLETF rats.
YM. Wang , K. Nagao, N. Inoue, Y. Ujino, Y. Shimada, T. Nagao, T. Iwata, T. Kamegai, Y. Yamauchi-Sato, T. Yanagita, Biosci. Biotechnol. Biochem., 70: 355-362 (2006) [PubMed]

Consumption of Pork-liver Protein Hydrolysate Reduces Body Fat in the Otsuka Long-Evans Tokushima Fatty Rats by Suppressing Hepatic Lipogenesis.
M. Shimizu, S. Tanabe, F. Morimatsu, K. Nagao, T. Yanagita, N. Kato, T. Nishimura, Biosci. Biotechnol. Biochem., 70: 112-118 (2006) [PubMed]



Conjugated linoleic acid-induced fatty liver can be attenuated by combination with docosahexaenoic acid in C57BL/6N mice.
T. Yanagita, YM. Wang, K. Nagao, Y. Ujino, N. Inoue, J. Agrc. Food Chem., 53: 9629-9633 (2005) [PubMed]

Short-term feeding of conjugated linoleic acid does not induce hepatic steatosis in C57BL/6J mice.
YM. Wang, K. Nagao, Y. Ujino, K. Sakata, K. Higa, N. Inoue, T. Yanagita, J. Nutr. Sci. Vitaminol., 51: 440-444 (2005) [PubMed]

Incorporation of branched-chain fatty acid into cellular lipids and caspase-independent apoptosis in human breast cancer cell line, SKBR-3.
S. Wongtangtintharn, H. Oku, H. Iwasaki, M. Inafuku, T. Toda, T. Yanagita, Lipids Health Dis., 4: 29 (2005) [PubMed]

Behavior of 11 organonitrogen pesticides during the refinement of edible oils. [Article in Japanese]
T. Fukazawa, Y. Suzuki, S. Tokairin, K. Chimi, T. Maruyama, T. Yanagita, J. Oleo Sci., 54: 431-435 (2005) [Publisher]

Conjugated fatty acids in food and their health benefits.
K. Nagao, T. Yanagita, J. Biosci. Bioeng., 100:152-157 (2005) [PubMed]

Dietary Phosphatidylcholine alleviates fatty liver induced by orotic acid.
Y. Buang, YM. Wang, JY. Cha, K. Nagao, T. Yanagita, Nutrition, 21:867-873 (2005) [PubMed]

Dietary gallate esters of tea catechins reduce deposition of visceral fat, hepatic triacylglycerol, and activities of hepatic enzymes related to Fatty Acid synthesis in rats.
I. Ikeda, R. Hamamoto, K. Uzu, K. Imaizumi, K. Nagao, T. Yanagita, Y. Suzuki, M. Kobayashi, T.Kakuda, Biosci. Biotechnol. Biochem., 69:1049-1053 (2005) [PubMed]

Dietary conjugated linoleic acid alleviates nonalcoholic fatty liver disease in Zucker (fa/fa) rats.
K. Nagao, N. Inoue, YM. Wang, B. Shirouchi, T. Yanagita, J. Nutr., 135: 9-13 (2005) [PubMed]



Determination of Trace Protein in Oils and Fats by Fluorescence Spectrophotometer. [Article in Japanese]
T. Fukazawa, S. Ishida, T. Maruyama, T. Yanagita, J. Oleo Sci., 53: 239-245 (2004) [Publisher]

Comparison of the lymphatic transport of radiolabeled 1,3-dioleoylglycerol and trioleoylglycerol in rats.
T. Yanagita, I. Ikeda, YM. Wang, H. Nakagiri, Lipids, 39: 827-832 (2004) [PubMed]

共役脂肪酸の生理機能.
柳田晃良, 王玉明, 永尾晃治, 水産学シリーズ142 「水産機能性脂質」, 133-144 (2004) [Publisher]

The 9cis,11trans,13cis isomer of conjugated linolenic acid reduces apolipoprotein B100 secretion and triacylglycerol synthesis in HepG2 cells.
K. Arao, H. Yotsumoto, SY. Han, K. Nagao, T. Yanagita, Biosci. Biotechnol. Biochem., 68:2643-2645 (2004) [PubMed]

Dietary effect of pomegranate seed oil rich in 9cis,11trans,13cis conjugated linolenic acid on lipid metabolism in obese, hyperlipidemic OLETF Rats.
K. Arao, YM. Wang, N. Inoue, J. Hirata, JY. Cha, K. Nagao, T. Yanagita, Lipids Health Dis., 3: 24 (2004) [PubMed]

Functional sulfur amino acid production and seawater remediation system by sterile Ulva sp. (Chlorophyta).
S. Hirayama, M. Miyasaka, H. Amano, Y. Kumagai, N. Shimojo, T. Yanagita, Y. Okami, Appl. Biochem. Biotechnol. 112: 101-110 (2004) [PubMed]

Conjugated linoleic acid prevents the development of essential hypertension in spontaneously hypertensive rats.
N. Inoue , K. Nagao, J. Hirata, YM. Wang, T. Yanagita, Biochem. Biophys. Res. Commun., 323: 679-684 (2004) [PubMed]

Alleviation of Fatty Liver by alpha-Linolenic Acid.
Y. Buang , JY. Cha, K. Nagao, YM. Wang, N. Inoue, T. Yanagita, J. Nutr. Sci. Vitaminol., 50: 272-276 (2004) [PubMed]

共役リノール酸の新規栄養生理機能.
永尾晃治, 柳田晃良, 日本栄養・食糧学会誌, 57:105-109 (2004) [Publisher]



Digestion and absorption of diacylglycerol.
T. Yanagita, I. Ikeda, Essential Fatty Acids and Eicosanoids, ed. by Y.S. Huang, S.J. Lin, P.C. Huang, AOCS press, USA, 316-320 (2003) [Publisher]

Effects of conjugated linoleic acid isomers on obesity and lipid metabolism in obese rats.
T. Yanagita, K. Nagao, YM. Wang, Essential Fatty Acids and Eicosanoids, ed. by Y.S. Huang, S.J. Lin, P.C. Huang, AOCS press, USA, 348-352 (2003) [Publisher]

Conjugated linoleic acid enhances plasma adiponectin level and alleviates hyperinsulinemia and hypertension in Zucker diabetic fatty (fa/fa) rats.
K. Nagao, N. Inoue, YM. Wang, T. Yanagita, Biochem. Biophys. Res. Commun., 310: 562-566 (2003) [PubMed]

共役リノール酸の抗肥満・抗高脂血症作用とその機序.
柳田晃良, 永尾晃治, 肥満研究, 9:194-196 (2003) [Publisher]

Purification of conjugated linoleic acid isomers through a process including lipase-catalyzed selective esterification.
T. Nagao, Y. Yamauchi-Sato, A. Sugihara, T. Iwata, K. Nagao, T. Yanagita, S. Adachi, Y. Shimada, Biosci. Biotechnol. Biochem., 67: 1429-1433 (2003) [PubMed]

The 10trans,12cis isomer of conjugated linoleic acid suppresses the development of hypertension in Otsuka Long-Evans Tokushima Fatty rats.
K. Nagao, N. Inoue, YM. Wang, Y. Buang, J. Hirata, T. Nagao, Y. Shimada, T. Matsui, T. Yanagita, Biochem. Biophys. Res. Commun., 306: 134-138 (2003) [PubMed]

The 10trans,12cis isomer of conjugated linoleic acid promotes energy metabolism in OLETF rats.
K. Nagao, YM. Wang, N. Inoue, SY. Han, Y. Buang, T. Noda, N. Koda, H. Okamatsu, T. Yanagita, Nutrition, 19: 652-656 (2003) [PubMed]

共役リノール酸の体脂肪低下作用.
柳田晃良, 永尾晃治, 食品工業, 46:18-24 (2003) [Publisher]

Conjugated linoleic acid reduces hepatic microsomal triacylglycerol transfer protein activity and hepatic triacylglycerol mass in obese rats.
YM. Wang, SM. Rahman, K. Nagao, SY. Han, Y. Buang, JY. Cha, T. Yanagita, J. Oleo Sci., 52: 129-134 (2003) [Publisher]

Comparison of the effects of triacylglycerol-CLA and free fatty acid-CLA on hepatic lipid metabolism in OLETF obese rats.
YM. Wang, SM. Rahman, K. Nagao, K Arao, N. Inoue, T. Yanagita, J. Oleo Sci., 52: 121-128 (2003) [Publisher]

Nutritional functions of dietary phosphatidylinositol.
T. Yanagita, INFORM, AOCS press, 14:64-66 (2003) [Publisher]

Cycloalliin, a cyclic sulfur imino acid, reduces serum triacylglycerol in rats.
T. Yanagita, SY. Han, YM. Wang, Y. Tsuruta, T. Anno, Nutrition, 19:140-143 (2003) [PubMed]



Sterol efflux to apolipoprotein A-I originates from caveolin-rich microdomains and potentiates PDGF-dependent protein kinase activity.
PE. Fielding, JS. Russel, TA. Spencer, H. Hakamata, K. Nagao, CJ. Fielding, Biochemistry, 41: 4929-4937 (2002) [PubMed]

Trans fatty acids in margarines marked in eleven countries.
H. Matsuzaki, T. Okamoto, M. Aoyama, T. Maruyama, I. Niiya, T. Yanagita, M. Sugano, J. Oleo Sci., 51: 555-561 (2002) [Publisher]

不稔性あおさ属植物を利用した沿岸海域浄化機能を有する有用物生産システムの提案.
平山伸, 宮坂政司, 天野秀臣, 熊谷嘉人, 下條信弘, 柳田晃良, 亀井勇統, 岡見吉郎, 日本海水学会誌, 56:158-162 (2002) [Publisher]

S-Propyl-cystein sulfoxide and DL-methionine sulfoxide inhibit the secretion of apolipoprotein B100 secretion and lipids in HepG2 cells.
SY. Han, T. Anno, N. Fukuda, K. Nagao,T. Yanagita, J. Oleo Sci., 51: 243-250 (2002) [Publisher]

S-Propyl cysteine reduces apolipoprotein B100 and triacylglycerol secretion in HepG2 cells.
SY. Han, T. Anno, T. Yanagita, Nutrition, 18: 505-509 (2002) [PubMed]



Feeding unsaponifiable compounds from rice bran oil dose not alter hepatic mRNA abundance for cholesterol metabolism-related proteins in hypercholesterolemic rats.
K. Nagao, M. Sato, M. Takenaka, M. Ando, M. Iwamoto, K. Imaizumi, Biosci. Biotech. Biochem., 65: 371-377 (2001) [PubMed]

Effects of short term adminstration of conjugated linoleic acid on lipid metabolism in white and brown adipose tissues of starved/refed OLETF rats.
SM. Rahman, YM. Wang, SY. Han, JY. Cha, H. Yotsumoto, T. Yanagita, Food Res. Int., 34: 515-520 (2001) [Publisher]

Effect of hesperitin, a citrus flavonoid, on the liver triacylglycerol content and phosphatidate phosphohydrolase activity in orotic acid-fed rats.
JY. Cha, YS. Cho, I. Kim、T. Anno, SM. Rahman,T. Yanagita, J. Plant Foods Human Nutr., 17: 1-10 (2001) [PubMed]

Effect of conjugated linoleic acid on serum leptin concentrations, body fat accumulation and beta-Oxidation of fatty acid in OLETF Rats.
SM. Rahman, YM. Wang, H. Yotsumoto, JY. Cha, S. Inoue, T. Yanagita, Nutrition, 17: 385-390 (2001) [PubMed]

油脂の特性と栄養生理機能.
柳田晃良, 王玉明, 科学と工業, 75:44-52 (2001) [Publisher]

Study of trans fatty acid content in commercial foods in Japan: VI chocolate and chocolate confectionery.
H. Matsuzaki, M. Aoyama, A. Baba, T. Maruyama, I. Niiya, T. Yanagita, M. Sugano, J. Oleo Sci., 50: 49-55 (2001) [Publisher]



A two-step mechanism for free cholesterol and phospholipid efflux from human vascular cells to apolipoprotein A-I.
PE. Fielding, K. Nagao, H. Hakamata, G. Chimini, CJ. Fielding, Biochemistry, 39: 14113-14120 (2000) [PubMed]

Superiority of dietary safflower oil over olive oil in lowering serum cholesterol and increasing hepatic mRNAs for LDL receptor and cholesterol 7alpha-hydroxylase in exogenously hypercholesterolemic (ExHC) rats.
M. Sato, S. Yoshida, K. Nagao, K. Imaizumi, Biosci. Biotech. Biochem., 64: 1111-1117 (2000) [PubMed]

Lymphatic lipid transport is not impaired in ageing rat intestine.
H. Hayashi, Y. Sato, S. Kanai, M. Masuda, M. Ohta, A. Funakoshi, K. Nagao, K. Imaizumi, K. Miyasaka, Mech. Ageing. Dev., 113: 219-225 (2000) [PubMed]

Application of the random arbitrary primed polymerase chain reaction differential display method to isolate genes of cholesterol metabolism-related proteins from rat liver.
M. Sato, S. Yoshida, K. Nagao, S. Nishizono, M. Kusaba, MC. Hung, I. Ikeda, K. Imaizumi, Biosci. Biotech. Biochem., 64: 1058-1060 (2000) [PubMed]

わが国の市販食品中のトランス型脂肪酸について(第5報)ー外国製スナックおよび菓子類ー.
松崎寿, 青山稔, 馬場明, 丸山武紀, 新谷勣, 柳田晃良, 菅野道廣, 日本油化学会誌, 49:625-60 (2000) [Publisher]

Lipid composition in long-day and short-day forms of the black bean aphid, Aphis fabae.
K. Itoyama, S. Tojo, T. Yanagita, J. Hardie, J. Insect Physiol., 46: 119-125 (2000) [PubMed]

タマネギ成分のニュトラスーティカルな作用.
柳田晃良, 韓瑞瑛, 阿武尚彦, バイオサイエンスとインダストリー, 58:855 (2000) [Publisher]


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